Depression in Parkinson's disease – a review
Identifieur interne : 000524 ( Main/Corpus ); précédent : 000523; suivant : 000525Depression in Parkinson's disease – a review
Auteurs : A. LiebermanSource :
- Acta Neurologica Scandinavica [ 0001-6314 ] ; 2006-01.
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Abstract
Major depression is present, at any given time, in 20–40% of Parkinson's disease (PD) patients, several times the prevalence in the general population. In addition, depression may precede the diagnosis of PD. These observations and reports of depression during deep brain stimulation of regions contiguous to the substantia nigra, as well as reports of dopamine agonist improving depression, suggest depression, rather than being mainly a psychological reaction to a debilitating disease, is part of PD. It is postulated that mesolimbic and mesocortical dopaminergic pathways that mediate affect, behavior, and cognition, contribute to depression in PD.
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DOI: 10.1111/j.1600-0404.2006.00536.x
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ISTEX:7BBD273A6061895E3ADE0D49FC6ECB4474F28491Le document en format XML
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Tel.: 1 305 403 4773
e‐mail: <email>al@liebermanparkinsonclinic.com</email></correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:ANE.ANE536.pdf"></link></linkGroup></publicationMeta><contentMeta><unparsedEditorialHistory>Accepted for publication February 10, 2005</unparsedEditorialHistory><countGroup><count type="figureTotal" number="0"></count><count type="tableTotal" number="0"></count></countGroup><titleGroup><title type="main">Depression in Parkinson's disease – a review</title><title type="shortAuthors"><b>Lieberman</b></title><title type="short"><b>Dopamine and depression</b></title></titleGroup><creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#aff-1-1"><personName><givenNames>A.</givenNames><familyName>Lieberman</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="aff-1-1" countryCode="US"><unparsedAffiliation>Lieberman Parkinson Clinic, North Bay Village, FL, USA</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en"><keyword xml:id="k1">Parkinson's disease</keyword><keyword xml:id="k2">depression</keyword><keyword xml:id="k3">dopamine</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><!-- Lieberman A. Depression in Parkinson's disease – a review.
Acta Neurol Scand 2006: 113: 1–8. © Blackwell Munksgaard 2006. --><p>Major depression is present, at any given time, in 20–40% of Parkinson's disease (PD) patients, several times the prevalence in the general population. In addition, depression may precede the diagnosis of PD. These observations and reports of depression during deep brain stimulation of regions contiguous to the substantia nigra, as well as reports of dopamine agonist improving depression, suggest depression, rather than being mainly a psychological reaction to a debilitating disease, is part of PD. It is postulated that mesolimbic and mesocortical dopaminergic pathways that mediate affect, behavior, and cognition, contribute to depression in PD.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Depression in Parkinson's disease – a review</title></titleInfo><titleInfo type="abbreviated"><title>Dopamine and depression</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Depression in Parkinson's disease – a review</title></titleInfo><name type="personal"><namePart type="given">A.</namePart><namePart type="family">Lieberman</namePart><affiliation>Lieberman Parkinson Clinic, North Bay Village, FL, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="review-article" displayLabel="reviewArticle"></genre><originInfo><publisher>Munksgaard International Publishers</publisher><place><placeTerm type="text">Oxford, UK</placeTerm></place><dateIssued encoding="w3cdtf">2006-01</dateIssued><edition>Accepted for publication February 10, 2005</edition><copyrightDate encoding="w3cdtf">2006</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">Major depression is present, at any given time, in 20–40% of Parkinson's disease (PD) patients, several times the prevalence in the general population. In addition, depression may precede the diagnosis of PD. These observations and reports of depression during deep brain stimulation of regions contiguous to the substantia nigra, as well as reports of dopamine agonist improving depression, suggest depression, rather than being mainly a psychological reaction to a debilitating disease, is part of PD. It is postulated that mesolimbic and mesocortical dopaminergic pathways that mediate affect, behavior, and cognition, contribute to depression in PD.</abstract><subject lang="en"><genre>Keywords</genre><topic>Parkinson's disease</topic><topic>depression</topic><topic>dopamine</topic></subject><relatedItem type="host"><titleInfo><title>Acta Neurologica Scandinavica</title></titleInfo><genre type="Journal">journal</genre><identifier type="ISSN">0001-6314</identifier><identifier type="eISSN">1600-0404</identifier><identifier type="DOI">10.1111/(ISSN)1600-0404</identifier><identifier type="PublisherID">ANE</identifier><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>113</number></detail><detail type="issue"><caption>no.</caption><number>1</number></detail><extent unit="pages"><start>1</start><end>8</end><total>8</total></extent></part></relatedItem><identifier type="istex">7BBD273A6061895E3ADE0D49FC6ECB4474F28491</identifier><identifier type="DOI">10.1111/j.1600-0404.2006.00536.x</identifier><identifier type="ArticleID">ANE536</identifier><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Munksgaard International Publishers</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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